To solve severe performance degradation problem of person re-identification task during cross-domain migration， a new cross-domain person re-identification method based on attention mechanism with learning intra-domain variance was proposed. Firstly， ResNet50 was used as the backbone network and some modifications were made to it， so that it was more suitable for person re-identification task. And Instance-Batch Normalization Network （IBN-Net） was introduced to improve the generalization ability of model. At the same time， for the purpose of learning more discriminative features， a region attention branch was added to the backbone network. For the training of source domain， it was treated as a classification task. Cross-entropy loss was utilized for supervised learning of source domain， and triplet loss was introduced to mine the details of source domain samples and improve the classification performance of source domain. For the training of target domain， intra-domain variance was considered to adapt the difference in data distribution between the source domain and the target domain. In the test phase， the output of ResNet50 pool-5 layer was used as image features， and Euclidean distance between query image and candidate image was calculated to measure the similarity of them. In the experiments on two large-scale public datasets of Market-1501 and DukeMTMC-reID， the Rank-1 accuracy of the proposed method is 80.1% and 67.7% respectively， and its mean Average Precision （mAP） is 49.5% and 44.2% respectively. Experimental results show that， the proposed method has better performance in improving generalization ability of model.